A specialty phase designed for SFC with a high density Diol surface coverage which ensures separations better and more reproducible than conventional unbonded silica. GreenSep Diol is particularly suitable for acidic and basic analytes.
GreenSep 4-Ethyl Pyridine is an alternative to and provides different selectivity to GreenSep Ethyl Pyridine (2- ethyl pyridine). The chromatogram below shows the separation of chemicals such as ibuprofen, ketoprofen and niflumic acid, without peak shape modifiers, and is a prime example of the superior peak shape performance obtainable with the GreenSep 4-Ethyl Pyridine column.
GreenSep FluoroBasic is based on fluorinated imidazole chemistry providing a highly basic and fluorinated character for this stationary phase. The addition of a fluorine groups into this stationary phase can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds. A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine.
GreenSep HILIC is composed of a polyhydroxylated polymer that is coated and bound to silica. This composition provides hydroxyl levels, that are well above conventional silica and diol type stationary phases, and permits higher loading.
GreenSep Amino Phenyl is a specialty SFC stationary phase that has proven superior to conventional stationary phases in the areas of separation selectivity and loading capacity which was designed for the separation of amines, alcohols and acids by SFC without the use of additives. Works well in Normal Phase mixed mode offering pi-pi interaction and exhibits good base deactivation.
The column ideally suited for the retention and rapid separation of chemicals containing acidic groups. Chemicals that contain acidic groups and demonstrate the retention and separation capability that GreenSep Ethyl Pyridine II can deliver for the SFC chromatographer.
GreenSep Naphthyl is based on the rigid structure of pi electron rich and the naphthalene molecule provides a basis for many diastereomeric separations. A naphthalene based SFC material, with high bonding density and intrinsic base deactivation due to a rigid structure that also enables the shape selectivity needed for many diastereomeric separations. It also exhibits strong π-π interaction and charge transfer interactions and performs well for diastereomers separations and non-polar compounds. The unique properties of GreenSep Naphthyl place its selectivity between graphitized carbon and alkyl type stationary phases.