ChromegaChiral CCO F4 T3 (4-Fluoro-3-(trifluoromethyl) phenyl cellulose) incorporates fluoro groups into its structure. The addition of a fluorine atom into a phenyl cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO-F4T3 is 4-Fluoro-3-(trifluoromethyl) phenyl cellulose phase can be used in SFC or HPLC.
ChromegaChiral CC3 (amylose tris(5-chloro-2-methyl- phenylcarbamate) is a new product for high resolution chiral separations based on a new halogenated carbohy- drate based chiral stationary phase. Similar in selectivity to ChiralPak® AY-H.
ChromegaChiral CCU is a modified amylose coated on high purity, high performance spherical silica particles. The chemical modification includes the combination of chemical bonding groups of methylbenzylcarbamate and 3-chloro-4 methylphenylcarbamate attached to amylose. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of amylose modified with phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures.
ChromegaChiral CCO is a polysaccharide coated chiral stationary phase and columns which are produced using a unique production process of coating the proven chiral selector, tris-(3,5-di-methylphenyl) carbamoyl cellulose on high purity, high performance silica. ChromegaChiral CCO columns are available in 3, 5, 10, and 20 micron particle sizes enabling easy scale up from analytical to preparative scale using HPLC or SFC conditions. Similar in selectivity to ChiralPak® OD.
Epic C4 SD is a highly base deactivated high carbon super dense (SD) phase that is produced via a multiple step process. The first step involves the HD bonding of monomeric C4 reagent. The second step utilizes a proprietary multiple endcapping bonding process that produces highly base deactivated columns. The Epic C4 SD product, as a result of our special bonding treatment, is highly hydrophobic and exceptionally inert for the analysis of both acids and bases. With our super dense bonding this product also has a wide pH range (1-12)