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GreenSep 4-Ethyl Pyridine II
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SKU: parent-123191-GS-PYE4-II
Categories: GreenSep 4-Ethyl Pyridine II, Super Critical Fluid (SFC) Columns
Tag: GreenSep
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GreenSep Ethyl Pyridine II
The column ideally suited for the retention and rapid separation of chemicals containing acidic groups. Chemicals that contain acidic groups and demonstrate the retention and separation capability that GreenSep Ethyl Pyridine II can deliver for the SFC chromatographer.
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Unlike many SFC columns which require the addition of amine modifiers to the mobile phase to improve peak shape for basic compounds, GreenSep DEAP does not, greatly simplifying mobile phase composition and fraction collection. This makes GreenSep DEAP the SFC column of choice for the retention and rapid separation of chemical compounds containing strong amine groups.
GreenSep 4-Ethyl Pyridine Prep
GreenSep 4-Ethyl Pyridine is an alternative to and provides different selectivity to GreenSep Ethyl Pyridine (2- ethyl pyridine). The chromatogram below shows the separation of chemicals such as ibuprofen, ketoprofen and niflumic acid, without peak shape modifiers, and is a prime example of the superior peak shape performance obtainable with the GreenSep 4-Ethyl Pyridine column.
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GreenSep HILIC is composed of a polyhydroxylated polymer that is coated and bound to silica. This composition provides hydroxyl levels, that are well above conventional silica and diol type stationary phases, and permits higher loading.
GreenSep Basic
GreenSep Basic exhibits a highly basic character and is ideally suited to high performance/high speed SFC preparative chromatography applications of chemicals containing amine groups. The chromatogram shown below contains chemicals that are functionalized with amine and acidic groups and is a prime example of the superior peak shape performance and separation capacity obtainable with the GreenSep Basic column. It also compares GreenSep Basic with GreenSep Ethyl Pyridine showing the superior reten- tion on GreenSep Basic when compared to GreenSep Ethyl Pyridine.
GreenSep FluoroBasic Prep
GreenSep FluoroBasic is based on fluorinated imidazole chemistry providing a highly basic and fluorinated character for this stationary phase. The addition of a fluorine groups into this stationary phase can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds. A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine.
GreenSep Ethyl Pyridine II Prep
The column ideally suited for the retention and rapid separation of chemicals containing acidic groups. Chemicals that contain acidic groups and demonstrate the retention and separation capability that GreenSep Ethyl Pyridine II can deliver for the SFC chromatographer.