A specialty phase designed for SFC with a high density Diol surface coverage which ensures separations better and more reproducible than conventional unbonded silica. GreenSep Diol is particularly suitable for acidic and basic analytes.
GreenSep FluoroBasic is based on fluorinated imidazole chemistry providing a highly basic and fluorinated character for this stationary phase. The addition of a fluorine groups into this stationary phase can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds. A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine.
The type of chemicals separated on a GreenSep Pyridyl Amide column would normally require the addition of TFA or an amine to the mobile phase as a peak shape modifier; however GreenSep Pyridyl Amide does not require this addition. Ideal for chemicals that contain both basic amine and acidic groups, as shown in the chromatogram below, GreenSep Pyridyl Amide provides flexibility for the SFC chromatographer with mobile phase composition and fraction collection greatly simplified without the use of amino additives.
GreenSep Nitro is a specifically designed SFC material for the separation of geometrical isomers and diastereomers. It is the column of choice in separating compounds that contain double bonds, aromatic groups, polarizable electrons and conjugated systems and exhibits a strong charge transfer system. GreenSep Nitro is unsurpassed for its separation capabilities and is available in analytical columns, preparative columns and bulk media.
GreenSep Amino Phenyl is a specialty SFC stationary phase that has proven superior to conventional stationary phases in the areas of separation selectivity and loading capacity which was designed for the separation of amines, alcohols and acids by SFC without the use of additives. Works well in Normal Phase mixed mode offering pi-pi interaction and exhibits good base deactivation.
The column ideally suited for the retention and rapid separation of chemicals containing acidic groups. Chemicals that contain acidic groups and demonstrate the retention and separation capability that GreenSep Ethyl Pyridine II can deliver for the SFC chromatographer.