ChromegaChiral CCO F4 T3 Prep

ChromegaChiral CCO F4 T3 (4-Fluoro-3-(trifluoromethyl) phenyl cellulose) incorporates fluoro groups into its structure. The addition of a fluorine atom into a phenyl cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO-F4T3 is 4-Fluoro-3-(trifluoromethyl) phenyl cellulose phase can be used in SFC or HPLC.

ChromegaChiral CCO is a polysaccharide coated chiral stationary phase and columns which are produced using a unique production process of coating the proven chiral selector, tris-(3,5-di-methylphenyl) carbamoyl cellulose on high purity, high performance silica. ChromegaChiral CCO columns are available in 3, 5, 10, and 20 micron particle sizes enabling easy scale up from analytical to preparative scale using HPLC or SFC conditions. Similar in selectivity to ChiralPak® OD.