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ChromegaChiral CCO F4 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO-F4 is an 4-Fluoro 3-methylphenyl cellulose phase which can be used in SFC or HPLC.
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