ChromegaChiral CCO F2 Prep

ChromegaChiral CCO F4 T3 (4-Fluoro-3-(trifluoromethyl) phenyl cellulose) incorporates fluoro groups into its structure. The addition of a fluorine atom into a phenyl cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO-F4T3 is 4-Fluoro-3-(trifluoromethyl) phenyl cellulose phase can be used in SFC or HPLC.

ChromegaChiral CCO F2 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO F2 is a 2-Fluoro 5-methylphenyl cellulose phase which can be used in SFC or HPLC.