ChromegaChiral CCA Prep

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A polysaccharide coated chiral stationary phase and columns which are produced using a unique production process of coating the proven chiral selector, tris-(3,5-di- methylphenyl) carbamoyl amylose on high purity silica gel. ChromegaChiral CCA columns, similar in selectivity to ChiralPak® AD, are available in 3, 5, 10, and 20 micron particle sizes enabling easy scale up from analytical to preparative scale using HPLC or SFC conditions.

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    ChromegaChiral CCS Prep

    ChromegaChiral CCS (amylose tris [(S)-α-methylbenzylcarbamate]) permits the enantiomeric separation of 1-Indanol without the addition of DEA (Diethyl amine). Historically DEA has been commonly used to improve peak shape for chiral separations of compounds such as 1-Indanol. ChromegaChiral CCS separates the 1-Indanol enantiomers with sharp peaks without DEA, providing superior chiral separations, sample loading and peak shape performance. Similar in selectivity to ChiralPak® AS-H.

    ChromegaChiral CC3 Prep

    ChromegaChiral CC3 (amylose tris(5-chloro-2-methyl- phenylcarbamate) is a new product for high resolution chiral separations based on a new halogenated carbohy- drate based chiral stationary phase. Similar in selectivity to ChiralPak® AY-H.

    ChromegaChiral CCX Prep

    ChromegaChiral CCX is a modified amylose coated on the high purity, high performance spherical silica particles. The chemical modification includes the combination of chemical bonding groups of methylbenzylcarbamate and 3,5-dimetheylphenylcarbamate attached to amylose. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of amylose modified with phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures.

    ChromegaChiral CC4

    ChromegaChiral CC4 (cellulose tris(4-chloro-3-methyl-phenylcarbamate) is another new product for high resolution chiral separations based on a new halogenated carbohydrate based chiral stationary phase. It is a modified cellulose coated on high purity, high performance spherical silica particles. The chemical modification includes the chemical bonding of 4-chloro-3 methylphenylcarbamate to cellulose. The use of cellulose modified with chlorinated phenyl groups provides a separation opportunity for many previously unresolved and poorly resolved chiral mixtures. Similar in selectivity to ChiralPak® OZ-H.

    ChromegaChiral CCC

    ChromegaChiral CCC is a modified cellulose including the combination of 3-chloro-4 methylphenylcarbamate and 3,5-dichloro- phenylcarbamate bonding groups coated on high purity, high performance spherical silica particles. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of cellulose modified with chlorinated phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures by providing unique separation characteristics.

    ChromegaChiral CCO F2 Prep

    ChromegaChiral CCO F2 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO F2 is a 2-Fluoro 5-methylphenyl cellulose phase which can be used in SFC or HPLC.

    ChromegaChiral CCU

    ChromegaChiral CCU is a modified amylose coated on high purity, high performance spherical silica particles. The chemical modification includes the combination of chemical bonding groups of methylbenzylcarbamate and 3-chloro-4 methylphenylcarbamate attached to amylose. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of amylose modified with phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures.

    ChromegaChiral CCO

    ChromegaChiral CCO is a polysaccharide coated chiral stationary phase and columns which are produced using a unique production process of coating the proven chiral selector, tris-(3,5-di-methylphenyl) carbamoyl cellulose on high purity, high performance silica. ChromegaChiral CCO columns are available in 3, 5, 10, and 20 micron particle sizes enabling easy scale up from analytical to preparative scale using HPLC or SFC conditions. Similar in selectivity to ChiralPak® OD.