Epic C18 is a highly base deactivated phase that produces the most inert silica C18 material available today. Because of the high density bonding levels (4umol/m2) this column demonstrates superior peak shapes for the most demanding tests. Epic C18 provides exceptional peak shape and selectivity over a wide pH range (pH 1-12).
Epic C18 SD sub-2 micron is specifically engineered for the demands of high performance HPLC. Epic C18-SD is a product of high bonding density technology; high bonding density provides the maximum stationary phase interaction providing a platform for flexible mobile phase compositions. It provides superior retention even at low and especially at high organic levels. In addition, it is compatible with all LC-MS mobile phases and buffer systems.
Epic HILIC-HC (HC for high capacity) is a new stationary phase for HILIC chromatography. It is composed of a polyhydroxylated polymer coated and bound to silica. This composition provides hydroxyl levels that are well above conventional hydroxyl and diol type stationary phases. Many of the commercially stationary phases used for HILIC chromatography are converted normal phase columns. These normal phase columns yield poor methods, poor separations and lack durability. Epic HILIC-HC is specifically designed for HILIC chromatography and can achieve high performance separations, yield rugged methods and deliver long column life times.
A baseline stabilized alkyl perfluorinated C8 – Epic FO-LB, with low bleed characteristics is well suited to the separation of trace impurities especially for halogenated analytes, lipophilic compounds and environmental samples.
Epic HILIC-FL is useful for retention and separation of polar and non-compounds. Reversed-phase HPLC is widely used for separation of many pharmaceutical compounds. However, retention and separation of many polar analytes has proven to be a challenge. Many of these types of compounds are unretained or poorly retained on most conventional reversed-phase stationary phases, such as ODS. Fortunately, to deal with these types of analytes an alternative mode of chromatography can be utilized using polar stationary phases and highly organic mobile phases. This mode of chromatography has been utilized for many years and is referred to as “hydrophilic interaction chromatography” or HILIC. HILIC chromatography uses mobile phases containing between 5 – 20 % water for the retention of polar compounds.