ChromegaChiral CC4

ChromegaChiral CC4 (cellulose tris(4-chloro-3-methyl-phenylcarbamate) is another new product for high resolution chiral separations based on a new halogenated carbohydrate based chiral stationary phase. It is a modified cellulose coated on high purity, high performance spherical silica particles. The chemical modification includes the chemical bonding of 4-chloro-3 methylphenylcarbamate to cellulose. The use of cellulose modified with chlorinated phenyl groups provides a separation opportunity for many previously unresolved and poorly resolved chiral mixtures. Similar in selectivity to ChiralPak® OZ-H.

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    ChromegaChiral CCO F2 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO F2 is a 2-Fluoro 5-methylphenyl cellulose phase which can be used in SFC or HPLC.

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    ChromegaChiral CCO F4 Prep

    ChromegaChiral CCO F4 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO-F4 is an 4-Fluoro 3-methylphenyl cellulose phase which can be used in SFC or HPLC.

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    ChromegaChiral CCA F4 Prep

    ChromegaChiral CCA F4 – The addition of a fluorine atom into a phenyl carbamate amylose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCA-F4 is an 4-Fluoro 3-methylphenyl amylose phase which can be used in SFC or HPLC.

    ChromegaChiral CCA

    A polysaccharide coated chiral stationary phase and columns which are produced using a unique production process of coating the proven chiral selector, tris-(3,5-di- methylphenyl) carbamoyl amylose on high purity silica gel. ChromegaChiral CCA columns, similar in selectivity to ChiralPak® AD, are available in 3, 5, 10, and 20 micron particle sizes enabling easy scale up from analytical to preparative scale using HPLC or SFC conditions.

    ChromegaChiral CCC Prep

    ChromegaChiral CCC is a modified cellulose including the combination of 3-chloro-4 methylphenylcarbamate and 3,5-dichloro- phenylcarbamate bonding groups coated on high purity, high performance spherical silica particles. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of cellulose modified with chlorinated phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures by providing unique separation characteristics.

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