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Chiral Separations Columns and Materials

Chirality has become critically important in the pharmaceutical, chemical, and agricultural industries. The subtle differences that make compounds chiral can produce dramatically different pharmacological effects in biological systems. As a result, the demand for stereoselective separation techniques and analytical assays to evaluate the enantiomeric purity of chiral compounds, has increased. Chiral chromatography in the forms of HPLC and SFC has become a necessary tool - not only for the analytical determination of enantiomeric purity, but also for the isolation and purification of enantiomers.

As a leader in chiral separations we are able to offer you a broad range of Chiral Stationary Phases (CSPs) for your analytical and preparative chromatography needs. Existing chiral stationary phases can separate a wide variety of chiral mixtures, however there are still enantiomeric mixtures that are difficult to separate limiting their characterization. This provides our drive to develop new CSP’s with differing chiral selectivities.

Product Features Include:

  • Excellent Selectivity Range
  • Wide Range of Applications
  • Superior Resolution and Efficiency
  • High Pressure Limit
  • Fast Optimization
  • One column for both SFC and HPLC use
Polysaccharide Coated CSPs

The chromatographic separation of chiral compounds is an important tool in the search for new pharmaceutical entities.

Pirkle Type Chiral Columns

ES Industries offer several different types of chiral stationary phases to handle the wide variety of chiral separation problems.