GreenSep Amino Phenyl
GreenSep Amino Phenyl is a specialty SFC stationary phase that has proven superior to conventional stationary phases in the areas of separation selectivity and loading capacity which was designed for the separation of amines, alcohols and acids by SFC without the use of additives. Works well in Normal Phase mixed mode offering pi-pi interaction and exhibits good base deactivation.
GreenSep Basic exhibits a highly basic character and is ideally suited to high performance/high speed SFC preparative chromatography applications of chemicals containing amine groups. The chromatogram shown below contains chemicals that are functionalized with amine and acidic groups and is a prime example of the superior peak shape performance and separation capacity obtainable with the GreenSep Basic column. It also compares GreenSep Basic with GreenSep Ethyl Pyridine showing the superior reten- tion on GreenSep Basic when compared to GreenSep Ethyl Pyridine.
Unlike many SFC columns which require the addition of amine modifiers to the mobile phase to improve peak shape for basic compounds, GreenSep DEAP does not, greatly simplifying mobile phase composition and fraction collection. This makes GreenSep DEAP the SFC column of choice for the retention and rapid separation of chemical compounds containing strong amine groups.
GreenSep Naphthyl is based on the rigid structure of pi electron rich and the naphthalene molecule provides a basis for many diastereomeric separations. A naphthalene based SFC material, with high bonding density and intrinsic base deactivation due to a rigid structure that also enables the shape selectivity needed for many diastereomeric separations. It also exhibits strong π-π interaction and charge transfer interactions and performs well for diastereomers separations and non-polar compounds. The unique properties of GreenSep Naphthyl place its selectivity between graphitized carbon and alkyl type stationary phases.
GreenSep Nitro is a specifically designed SFC material for the separation of geometrical isomers and diastereomers. It is the column of choice in separating compounds that contain double bonds, aromatic groups, polarizable electrons and conjugated systems and exhibits a strong charge transfer system. GreenSep Nitro is unsurpassed for its separation capabilities and is available in analytical columns, preparative columns and bulk media.
Specifically designed for the separation of geometrical isomers as well as diastereomers. It is the column of choice in separating compounds that contain aromatic groups, polarizable electrons and conjugate systems. In addition, GreenSep PFP is useful for the separation of halogenated compounds. In many cases GreenSep PFP provides orthogonal separations when compared to GreenSep Nitro. GreenSep PFP is unsurpassed for its separation capabilities and is available in analytical columns, preparative columns and bulk media.
GreenSep Pyridyl Amide
The type of chemicals separated on a GreenSep Pyridyl Amide column would normally require the addition of TFA or an amine to the mobile phase as a peak shape modifier; however GreenSep Pyridyl Amide does not require this addition. Ideal for chemicals that contain both basic amine and acidic groups, as shown in the chromatogram below, GreenSep Pyridyl Amide provides flexibility for the SFC chromatographer with mobile phase composition and fraction collection greatly simplified without the use of amino additives.
GreenSep Silica is a metal free, ultra high purity chromatographic media that is pressure stable and specifically engineered for high performance SFC separations. The surface is treated to produce optimum SFC separation interactions and loading capacity while maintaining superior peak shape perfor- mance for many chemicals. GreenSep Silica is available for analytical and preparative column formats in particle sizes from 1.8 μm to 20 μm.