ChromegaChiral CC2 Prep
ChromegaChiral CC2 is a modified cellulose including 3-chloro-4 methylphenyl-carbamate bonding groups coated on high purity, high performance spherical silica particles. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases and provides for similar separation behavior to Phenomenex Lux® Cellulose-2.
ChromegaChiral CC3 Prep
ChromegaChiral CC3 (amylose tris(5-chloro-2-methyl- phenylcarbamate) is a new product for high resolution chiral separations based on a new halogenated carbohy- drate based chiral stationary phase. Similar in selectivity to ChiralPak® AY-H.
ChromegaChiral CC4 Prep
ChromegaChiral CC4 (cellulose tris(4-chloro-3-methyl-phenylcarbamate) is another new product for high resolution chiral separations based on a new halogenated carbohydrate based chiral stationary phase. It is a modified cellulose coated on high purity, high performance spherical silica particles. The chemical modification includes the chemical bonding of 4-chloro-3 methylphenylcarbamate to cellulose. The use of cellulose modified with chlorinated phenyl groups provides a separation opportunity for many previously unresolved and poorly resolved chiral mixtures. Similar in selectivity to ChiralPak® OZ-H.
ChromegaChiral CCA F4 Prep
ChromegaChiral CCA F4 – The addition of a fluorine atom into a phenyl carbamate amylose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCA-F4 is an 4-Fluoro 3-methylphenyl amylose phase which can be used in SFC or HPLC.
ChromegaChiral CCA Prep
A polysaccharide coated chiral stationary phase and columns which are produced using a unique production process of coating the proven chiral selector, tris-(3,5-di- methylphenyl) carbamoyl amylose on high purity silica gel. ChromegaChiral CCA columns, similar in selectivity to ChiralPak® AD, are available in 3, 5, 10, and 20 micron particle sizes enabling easy scale up from analytical to preparative scale using HPLC or SFC conditions.
ChromegaChiral CCC Prep
ChromegaChiral CCC is a modified cellulose including the combination of 3-chloro-4 methylphenylcarbamate and 3,5-dichloro- phenylcarbamate bonding groups coated on high purity, high performance spherical silica particles. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of cellulose modified with chlorinated phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures by providing unique separation characteristics.
ChromegaChiral CCJ Prep
ChromegaChiral CCJ (cellulose 4-methylbenzoate) is a new product for high resolution chiral separations based on a new halogenated carbohydrate based chiral stationary phase. Similar in selectivity to ChiralPak® OJ-H.
ChromegaChiral CCO F2 Prep
ChromegaChiral CCO F2 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO F2 is a 2-Fluoro 5-methylphenyl cellulose phase which can be used in SFC or HPLC.
ChromegaChiral CCO F4 Prep
ChromegaChiral CCO F4 – The addition of a fluorine atom into a phenyl carbamate cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particularly useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO-F4 is an 4-Fluoro 3-methylphenyl cellulose phase which can be used in SFC or HPLC.
ChromegaChiral CCO F4 T3 Prep
ChromegaChiral CCO F4 T3 (4-Fluoro-3-(trifluoromethyl) phenyl cellulose) incorporates fluoro groups into its structure. The addition of a fluorine atom into a phenyl cellulose structure can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds (1). A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine (2). ChromegaChiral CCO-F4T3 is 4-Fluoro-3-(trifluoromethyl) phenyl cellulose phase can be used in SFC or HPLC.
ChromegaChiral CCO Prep
ChromegaChiral CCO is a polysaccharide coated chiral stationary phase and columns which are produced using a unique production process of coating the proven chiral selector, tris-(3,5-di-methylphenyl) carbamoyl cellulose on high purity, high performance silica. ChromegaChiral CCO columns are available in 3, 5, 10, and 20 micron particle sizes enabling easy scale up from analytical to preparative scale using HPLC or SFC conditions. Similar in selectivity to ChiralPak® OD.
ChromegaChiral CCS Prep
ChromegaChiral CCS (amylose tris [(S)-α-methylbenzylcarbamate]) permits the enantiomeric separation of 1-Indanol without the addition of DEA (Diethyl amine). Historically DEA has been commonly used to improve peak shape for chiral separations of compounds such as 1-Indanol. ChromegaChiral CCS separates the 1-Indanol enantiomers with sharp peaks without DEA, providing superior chiral separations, sample loading and peak shape performance. Similar in selectivity to ChiralPak® AS-H.
ChromegaChiral CCU Prep
ChromegaChiral CCU is a modified amylose coated on high purity, high performance spherical silica particles. The chemical modification includes the combination of chemical bonding groups of methylbenzylcarbamate and 3-chloro-4 methylphenylcarbamate attached to amylose. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of amylose modified with phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures.
ChromegaChiral CCX Prep
ChromegaChiral CCX is a modified amylose coated on the high purity, high performance spherical silica particles. The chemical modification includes the combination of chemical bonding groups of methylbenzylcarbamate and 3,5-dimetheylphenylcarbamate attached to amylose. This combination of bonded groups stabilizes the solubility of coated phase making for a durable phase similar to other widely used coated phases. The use of amylose modified with phenyl groups provides for the separation for many previously unresolved/poorly resolved chiral mixtures.
Epic Amine HD Prep
The Epic bonding technology produces columns of superior performance and durability. These performance characteristics result from the high bonding density found in the Epic bonding process.
Epic Biphenyl Prep
Epic Biphenyl is a truly unique stationary phase with properties significantly different than ODS phases. This unique character results from bonded biphenyl group imparting a pi-pi electron interaction which produces an enhanced retention for many compounds particularly those that contain polarizable electrons. Many classes of compounds contain polarizable electrons including halogenated compounds, aromatics, nitro aromatics and conjugated systems.
Epic C12 Prep
The Epic bonding technology produces columns of superior performance and durability. These performance characteristics result from the high bonding density found in the Epic bonding process.
Epic C18 MS Prep
Epic C18 MS provides superior retention even at high organic levels. Many LC-MS applications rely on high level of organic modifier in the mobile phase, particularly in the for high performance trace analysis requiring high sensitivity and low level detection
Epic C18 Prep
Epic C18 is a highly base deactivated phase that produces the most inert silica C18 material available today. Because of the high density bonding levels (4umol/m2) this column demonstrates superior peak shapes for the most demanding tests. Epic C18 provides exceptional peak shape and selectivity over a wide pH range (pH 1-12).
Epic C4 SD Prep
Epic C4 SD is a highly base deactivated high carbon super dense (SD) phase that is produced via a multiple step process. The first step involves the HD bonding of monomeric C4 reagent. The second step utilizes a proprietary multiple endcapping bonding process that produces highly base deactivated columns. The Epic C4 SD product, as a result of our special bonding treatment, is highly hydrophobic and exceptionally inert for the analysis of both acids and bases. With our super dense bonding this product also has a wide pH range (1-12)
Epic C8 Prep
Epic C8 is a highly base deactivated phase that produces the most inert silica C8 material available today. Because of the high density bonding levels (4umol/m2) this column demonstrates superior peak shapes for the most demanding tests. Epic C8 provides exceptional peak shape and selectivity over a wide pH range (pH 1-12).
Epic Cyano Prep
The Epic bonding technology produces columns of superior performance and durability. These performance characteristics result from the high bonding density found in the Epic bonding process.
Epic Diol Prep
The Epic bonding technology produces columns of superior performance and durability. These performance characteristics result from the high bonding density found in the Epic bonding process.
Epic Diphenyl Prep
Epic Diphenyl bonded phase, with reduced hydrophobicity produces HPLC columns with novel selectivity, exhibiting increased speed and resolution, utilizes strong dipole‐dipole hydrogen bonding and π‐π mechanisms for different selectivity for compounds containing double bonds or aromatic functional groups. In addition, the diphenyl arrangement of the phase can also contribute to steric selectivity allowing for an additional chromatographic interaction. Epic Diphenyl is also highly selective for proteins with aromatic side chains and may be used as a USP L11 column.
Epic FDD Prep
The Epic bonding technology produces columns of superior performance and durability. These performance characteristics result from the high bonding density found in the Epic bonding process.
Epic FO LB Prep
A baseline stabilized alkyl perfluorinated C8 – Epic FO-LB, with low bleed characteristics is well suited to the separation of trace impurities especially for halogenated analytes, lipophilic compounds and environmental samples.
Epic HILIC FL Prep
Epic HILIC-FL is useful for retention and separation of polar and non-compounds. Reversed-phase HPLC is widely used for separation of many pharmaceutical compounds. However, retention and separation of many polar analytes has proven to be a challenge. Many of these types of compounds are unretained or poorly retained on most conventional reversed-phase stationary phases, such as ODS. Fortunately, to deal with these types of analytes an alternative mode of chromatography can be utilized using polar stationary phases and highly organic mobile phases. This mode of chromatography has been utilized for many years and is referred to as “hydrophilic interaction chromatography” or HILIC. HILIC chromatography uses mobile phases containing between 5 – 20 % water for the retention of polar compounds.
Epic HILIC HC Prep
Epic HILIC-HC (HC for high capacity) is a new stationary phase for HILIC chromatography. It is composed of a polyhydroxylated polymer coated and bound to silica. This composition provides hydroxyl levels that are well above conventional hydroxyl and diol type stationary phases. Many of the commercially stationary phases used for HILIC chromatography are converted normal phase columns. These normal phase columns yield poor methods, poor separations and lack durability. Epic HILIC-HC is specifically designed for HILIC chromatography and can achieve high performance separations, yield rugged methods and deliver long column life times.
Epic HILIC PI Prep
Epic HILIC-PI is a new stationary phase for HILIC chromatography. It consists of an aromatic amine based stationary phase bound to silica. This composition provides for excellent retention and peak shape for polar amine compounds. Many of the commercially available HILIC stationary phases are converted normal phase columns. These normal phase columns yield poor methods, poor separations and lack durability. Epic HILIC-PI is specifically designed for HILIC chromatography and can achieve high performance separations, yield rugged methods and deliver long column life times. Epic HILIC-PI is an excellent choice for samples containing polar amines were superior retention and peak shape are essential.