Epic HILIC PI Prep

Epic HILIC-PI is a new stationary phase for HILIC chromatography. It consists of an aromatic amine based stationary phase bound to silica. This composition provides for excellent retention and peak shape for polar amine compounds. Many of the commercially available HILIC stationary phases are converted normal phase columns. These normal phase columns yield poor methods, poor separations and lack durability. Epic HILIC-PI is specifically designed for HILIC chromatography and can achieve high performance separations, yield rugged methods and deliver long column life times. Epic HILIC-PI is an excellent choice for samples containing polar amines were superior retention and peak shape are essential.

Epic HILIC RP Prep

Epic HILIC-RP is a new stationary phase for a combination of HILIC and reverse phase chromatography. It is a combination of a polyhydroxylated polymer coated and bound to silica and ODS groups also bound to silica. This composition provides hydroxyl levels that are well above conventional hydroxyl and diol type stationary phases. Many of the commercially stationary phases used for HILIC chromatography are converted normal phase columns. These normal phase columns yield poor methods, poor separations and lack durability. Epic HILIC-RP is specifically designed for HILIC chromatography and can achieve high performance separations, yield rugged methods and deliver long column life times. Epic HILIC-RP is an excellent choice for samples containing polar and hydrophobic analytes.

Epic HILIC Silica Prep

Epic HILIC Silica columns have been specifically developed for HILIC chromatography. The combination of tight particle size control and high specific surface area deliver superior performance for HILIC separations.

Epic Naphthyl Prep

Epic Naphthyl is a naphthalene based material, with high bonding density and intrinsic base deactivation due to a rigid structure that also enables the shape selectivity needed for many diastereomeric separations. It exhibits strong π-π interaction and charge transfer interactions and performs well for diastereomers separations and non-polar compounds. The unique properties of Epic Naphthyl places its selectivity between graphitized carbon and alkyl type stationary phases.

Epic PFP LB Prep

The Epic PFP-LB is a pentafluorophenyl that has been baseline stabilized and is ready for high performance separations for a number of applications including the separation of natural products, halogenated compounds, aromatics, conjugated compounds and trace impurities in complex matrices. Many of these high performance separations were not possible with existing PFP columns especially in the area of trace impurities where baseline bleed levels were unacceptable.

Epic Phenyl Hexyl Prep

Epic Phenyl-Hexyl uses a hexyl-linked phenyl phase. The hexyl alkyl chain provides for unique selectivity and increased hydrolytic stability when compared to propyl-linked chemistry. The Epic high-density bonding technology delivers to the chromatographer superior performance, durability, and enhanced lot-to-lot reproducibility. Epic Phenyl-Hexyl offers the chromatographer a truly superior phenyl based interaction for enhanced chromatographic performance.

Epic Phenyl Prep

The Epic bonding technology produces columns of superior performance and durability. These performance characteristics result from the high bonding density found in the Epic bonding process.

Epic Polar Prep

Epic Polar is a high density C18 packing specifically engineered for the retention of polar analytes. Epic Polar is a reversed phase column that enables highly soluble solutes to fully interact with the bonded hydrocarbon phase, even in pure aqueous mobile phases. Under these highly aqueous conditions, our novel proprietary bonding chemistry allows the bonded chains to remain fully extended in the mobile phase. Epic Polar is a true base deactivated reverse phase column and does not contain any undesirable ion exchange or mixed mode characteristics. Epic Polar can retain highly water-soluble compounds such as small organic acids, water-soluble vitamins, purines and pyrimidines, cathecholamines and other polar compounds.

Epic Polar XP Prep

The Epic Polar XP ODS phase has been specifically developed using patented technology for use with highly aqueous mobile phases, including 100% aqueous, along with a specially developed propriety endcapping technology. Our unique patented approach provides a complete solution to ensure that Epic Polar XP is totally resistant to “phase collapse” under all mobile phase conditions and is able to deliver superior peak performance for amine containing compounds. In addition, Epic Polar XP can be used with any routinely used mobile phase modifier such as acetonitrile, methanol etc.

Epic SCX Prep

Epic SCX is a strong cation exchanger on a silica base. It’s suitable for the analysis of organic bases or as a trap column for two dimensional HPLC. Epic SCX utilizes the high density bonding technology which provides for superior cation loading and robustness. Epic SCX is based on bonded aromatic sulfonic acid groups and is available in 10, 5, 3 and 1.8 um particle sizes. Epic SCX will provide for the best performance of any silica based cation exchanger. Epic SCX has an exchange capacity of 3meq/gram making it the strongest silica based cation exchanger available. A separation of four nucleosides is shown below using only ammonium formate as a mobile phase.

Epic Silica Prep

Epic Silica is the backbone for the EPIC bonded product range and is a 120 Angstrom high purity metal free synthetic silica.

FluoroSep-RP Octyl

Unique Reverse Phase Interaction – FluoroSep-RP Octyl contains bonded perfluorooctyl groups and were designed to separate closely related structural isomers. FluoroSep-RP columns resolve many compounds of pharmaceutical and agricultural interest, especially halogenated molecules. The perfluorinated stationary pyhase is less hydrophobic than a C8 or C18, with a unique selectivity to achieve difficult separations with simple isocratic mobile phases.

FluoroSep-RP Phenyl

FluoroSep-RP Phenyl is a truly unique stationary phase with properties significantly different than ODS phases. This unique character results from bonded pentafluorophenyl groups imparting a pi-pi electron interaction which produces an enhanced retention for many compounds particularly those that contain polarizable electrons. Many classes of compounds contain polarizable electrons including halogenated compounds, aromatics, and conjugated systems. Many naturally occurring chemicals also contain polarizable electrons and can be separated using FluoroSep-RP Phenyl. 

FluoroSep-RP Phenyl HS

FluoroSep-RP Phenyl HS is a high surface area ersion of FluoroSep-RP Phenyl and is a truly unique stationary phase with properties significantly different than ODS phases. This unique character results from bonded pentafluorophenyl groups imparting a pi-pi electron interaction which produces an enhanced retention for many compounds particularly those that contain polarizable electrons. Many classes of compounds contain polarizable electrons including halogenated compounds, aromatics, and conjugated systems. Many naturally occurring chemicals also contain polarizable electrons and can be separated using FluoroSep-RP Phenyl. 

FluoroSep-RP Propyl

FluoroSep-RP Propyl (FP) contains monomerically bonded perfluoropropyl groups. FP is high efficiency short chain phase used for the separation of proteins, peptides, and other related compounds of medicinal/biological interest.

GammaBond Alumina RP1

GammaBond Alumina is a family of exceptionally stable alumina-based HPLC columns designed for extreme pH applications to provide high efficiency and unique selectivity. GammaBond Alumina is manufactured by bonding a polymer to a highly stable porous spherical 5 μm alumina particle. This proprietary manufacturing process yields polymercoated packings with the same high efficiency as traditional silica columns, but with all the advantages of alumina. GammaBond reversed phase columns may be used with any mobile phase from pH 1.3 to pH 12, and any desired buffer system or additive. GammaBond RP-1 is used for USP method L-29.

GreenSep 4-Ethyl Pyridine Prep

GreenSep 4-Ethyl Pyridine is an alternative to and provides different selectivity to GreenSep Ethyl Pyridine (2- ethyl pyridine). The chromatogram below shows the separation of chemicals such as ibuprofen, ketoprofen and niflumic acid, without peak shape modifiers, and is a prime example of the superior peak shape performance obtainable with the GreenSep 4-Ethyl Pyridine column.

GreenSep Amino Phenyl Prep

GreenSep Amino Phenyl is a specialty SFC stationary phase that has proven superior to conventional stationary phases in the areas of separation selectivity and loading capacity which was designed for the separation of amines, alcohols and acids by SFC without the use of additives. Works well in Normal Phase mixed mode offering pi-pi interaction and exhibits good base deactivation.

GreenSep Basic Prep

GreenSep Basic exhibits a highly basic character and is ideally suited to high performance/high speed SFC preparative chromatography applications of chemicals containing amine groups. The chromatogram shown below contains chemicals that are functionalized with amine and acidic groups and is a prime example of the superior peak shape performance and separation capacity obtainable with the GreenSep Basic column. It also compares GreenSep Basic with GreenSep Ethyl Pyridine showing the superior reten- tion on GreenSep Basic when compared to GreenSep Ethyl Pyridine.

GreenSep Cyano Prep

GreenSep Cyano is a high surface area Cyano bonded material designed for SFC resulting in a high surface area loading.

GreenSep DEAP Prep

Unlike many SFC columns which require the addition of amine modifiers to the mobile phase to improve peak shape for basic compounds, GreenSep DEAP does not, greatly simplifying mobile phase composition and fraction collection. This makes GreenSep DEAP the SFC column of choice for the retention and rapid separation of chemical compounds containing strong amine groups.

GreenSep Diol Prep

A specialty phase designed for SFC with a high density Diol surface coverage which ensures separations better and more reproducible than conventional unbonded silica. GreenSep Diol is particularly suitable for acidic and basic analytes.

GreenSep Ethyl Pyridine II Prep

The column ideally suited for the retention and rapid separation of chemicals containing acidic groups. Chemicals that contain acidic groups and demonstrate the retention and separation capability that GreenSep Ethyl Pyridine II can deliver for the SFC chromatographer.

GreenSep FluoroBasic Prep

GreenSep FluoroBasic is based on fluorinated imidazole chemistry providing a highly basic and fluorinated character for this stationary phase. The addition of a fluorine groups into this stationary phase can be useful in promoting fluorophilic retention mechanism which can provide improved retention for fluorinated compounds. A fluorophilic retention mechanism can be particular useful in medicinal chemistry and drug discovery, where more than a third of newly approved small molecule drugs contain fluorine.

GreenSep HILIC Prep

GreenSep HILIC is composed of a polyhydroxylated polymer that is coated and bound to silica. This composition provides hydroxyl levels, that are well above conventional silica and diol type stationary phases, and permits higher loading.

GreenSep Naphthyl Prep

GreenSep Naphthyl is based on the rigid structure of pi electron rich and the naphthalene molecule provides a basis for many diastereomeric separations. A naphthalene based SFC material, with high bonding density and intrinsic base deactivation due to a rigid structure that also enables the shape selectivity needed for many diastereomeric separations. It also exhibits strong π-π interaction and charge transfer interactions and performs well for diastereomers separations and non-polar compounds. The unique properties of GreenSep Naphthyl place its selectivity between graphitized carbon and alkyl type stationary phases.

GreenSep Nitro Prep

GreenSep Nitro is a specifically designed SFC material for the separation of geometrical isomers and diastereomers. It is the column of choice in separating compounds that contain double bonds, aromatic groups, polarizable electrons and conjugated systems and exhibits a strong charge transfer system. GreenSep Nitro is unsurpassed for its separation capabilities and is available in analytical columns, preparative columns and bulk media.

GreenSep NP-I

GreenSep NP-I has been specifically optimized for the separation of 10 different Cannabinoids. This stationary phase has proven superior to conventional stationary phases (such as diol, cyano etc…) in the areas of separation selectivity and peak shape.