LiChrosorb RP8

LiChrosorb RP8 is a octyl phase bonded to LiChrosorb Silica material. LiChrosorb, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrosorb is a high quality irregular silica with a high surface area and excellent loadability. LiChrosorb is offered in a wide range of bonded phases. 

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LiChrosorb RP8 Endcapped

LiChrosorb RP8 Endcapped is an octyl phase bonded to LiChrosorb Silica material which is endcapped. LiChrosorb, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrosorb is a high quality irregular silica with a high surface area and excellent loadability. LiChrosorb is offered in a wide range of bonded phases. 

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LiChrosorb Silica 60

LiChrosorb Silica 60, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrosorb is a high quality irregular silica with a high surface area and excellent loadability. LiChrosorb is offered in a wide range of bonded phases. 

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LiChrospher Diol

LiChrospher Diol is a diol phase bonded to LiChrospher Silica material. LiChrospher, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrospher is a high quality spherical silica with a high surface area and excellent loadability. LiChrospher is offered in a wide range of bonded phases. 

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LiChrospher RP18

LiChrospher RP18 is a octadecyl phase bonded to LiChrospher Silica material. LiChrospher, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrospher is a high quality spherical silica with a high surface area and excellent loadability. LiChrospher is offered in a wide range of bonded phases. 

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LiChrospher RP18 Endcapped

LiChrospher RP18 is an endcapped octadecyl phase bonded to LiChrospher Silica material. LiChrospher, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrospher is a high quality spherical silica with a high surface area and excellent loadability. LiChrospher is offered in a wide range of bonded phases. 

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LiChrospher RP8

LiChrospher RP8 is a octyl phase bonded to LiChrospher Silica material. LiChrospher, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrospher is a high quality spherical silica with a high surface area and excellent loadability. LiChrospher is offered in a wide range of bonded phases. 

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LiChrospher Silica 60

LiChrospher Silica 60 material. LiChrospher, manufactured by E. Merck, Germany for over 35 years and well documented in the literature. LiChrospher is a high quality spherical silica with a high surface area and excellent loadability. LiChrospher is offered in a wide range of bonded phases. 

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MacroDac C18

MacroDac™ C18 is an excellent alternative to W.R. Grace VYDAC® wide pore C18 chromatography media. MacroDac™ C18 is the ideal medium for high-performance reversed-phase chromatography of proteins, peptides, and other large molecules that had previously been difficult to separate by reversed-phase HPLC procedures. The large pores of the 300Å silica allow polypeptide molecules complete access to the interior of the silica pores. MacroDac™ C18 reversed-phase material consists of octadecyl aliphatic groups bonded to the surface of 300Å pore diameter silica. The unique process by which we manufacture MacroDac™ C18 provides for an HPLC media with very high purity synthetic silica and carefully controlled characteristics. The hydrophobic (reversed) phase is attached to the silica using polyfunctional octadecylchlorosilanes resulting in cross-linking, or polymerization of the hydrophobic phase.

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MacroDac C4

MacroDac™ C4 is an excellent alternative to W.R. Grace VYDAC® wide pore C4 chromatography media. MacroDac™ C4 is the ideal medium for high-performance reversed-phase chromatography of proteins, peptides, and other large molecules that had previously been difficult to separate by reversed-phase HPLC procedures. The large pores of the 300Å silica allow polypeptide molecules complete access to the interior of the silica pores. MacroDac™ C4 reversed-phase material consists of butyl aliphatic groups bonded to the surface of 300Å pore diameter silica. The unique process by which we manufacture MacroDac™ C4 provides for an HPLC media with very high purity synthetic silica and carefully controlled characteristics. The hydrophobic (reversed) phase is attached to the silica using polyfunctional butylchlorosilanes resulting in cross-linking, or polymerization of the hydrophobic phase.

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MacroDac C8

MacroDac™ C8 is an excellent alternative to W.R. Grace VYDAC® wide pore C8 chromatography media. MacroDac™ C8 is the ideal medium for high-performance reversed-phase chromatography of proteins, peptides, and other large molecules that had previously been difficult to separate by reversed-phase HPLC procedures. The large pores of the 300Å silica allow polypeptide molecules complete access to the interior of the silica pores. MacroDac™ C8 reversed-phase material consists of octyl aliphatic groups bonded to the surface of 300Å pore diameter silica. The unique process by which we manufacture MacroDac™ C8 provides for an HPLC media with very high purity synthetic silica and carefully controlled characteristics. The hydrophobic (reversed) phase is attached to the silica using polyfunctional octylchlorosilanes resulting in cross-linking, or polymerization of the hydrophobic phase.

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MacroSep BIO AQS

MacroSep BIO AQS consists of ether linked aliphatic groups bonded to the surface of 300Å pore diameter ultrahigh purity silica. MacroSep BIO AQS is phase collapse resistant with highly aqueous mobile phases. MacroSep BIO AQS can be used to separate glycoproteins, peptides, tryptic digests, and hemoglobin variants.

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MacroSep BIO C18

MacroSep BIO C18 consists of n-octadecyl aliphatic groups bonded to the surface of 300Å pore diameter ultra-high purity silica. MacroSep BIO C18 can be used to separate small polypeptides, tryptic digests, synthetic peptides, and natural peptides.

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MacroSep BIO C4

MacroSep BIO C4 consists of butyl aliphatic groups bonded to the surface of 300Å pore diameter ultra-high purity silica. MacroSep BIO C4 can be used to separate glycoproteins, peptides, hemoglobin variants, human growth hormone and membrane proteins.

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MacroSep BIO C8

MacroSep BIO C8 consists of n-octyl aliphatic groups bonded to the surface of 300Å pore diameter ultra-high purity silica. MacroSep BIO C8 can be used to separate peptides and digest fragments.

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MacroSep BIO Cyano

MacroSep BIO Cyano based upon ultra-high purity metal free silica containing highly controlled pores of 300Å pore diameter.This column technology is a superior tool for the analysis of proteins, peptides and other biomolecules.

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MacroSep BIO HPR

MacroSep HPR can be used to separate large hydrophobic proteins, lipid peptides, polypeptide with aliphatic side chains and membrane-spanning peptides.

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MacroSep BIO-Gold BiPhenyl

MacroSep BIO Gold Biphenyl – very good bonding density, less hydrophobic than the Naphthyl and provides excellent pi-pi interactions. Used to separate bio-pharmaceuticals and biologicals. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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MacroSep BIO-Gold C18

MacroSep BIO Gold C18 – a hydrophobic phase ideal for the separation of high molecular weight peptides and oligonucleic acids. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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MacroSep BIO-Gold C4

MacroSep BIO Gold C4 – least hydrophobic of all the alkyl MacroSep BIO phases (ODS & C8) and may be used for hydrophilic proteins and BIO-polymers. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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MacroSep BIO-Gold C8

MacroSep BIO Gold C8 – less hydrophobic and may yield faster separations when compared to C18 and is used to separate many classes of compounds including bio-pharmaceuticals and biologicals. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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MacroSep BIO-Gold DiPhenyl

MacroSep BIO Gold Diphenyl – the lowest bonding density and one of the lowest hydrophobicities of any BIO Gold Phenyl phases. Provides some site specific phenyl interactions dependant on the molecular configuration of the target. Resolves many classes of proteins and bio-polymers. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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MacroSep BIO-Gold HPR

MacroSep BIO Gold HPR significantly reduces the hydrophobic interaction of the stationary phase. This reduced interaction can yield less retention of hydrophobic biological molecules yielding better recoveries and quicker separations. HPR is the most hydrophilic of the MacroSep BIO Gold phases and may be useful for fluorine modified biologics based upon a fluorophilicity interaction. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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MacroSep BIO-Gold Naphthyl

MacroSep BIO Gold Naphthyl – highest bonding density resulting in an inert and stable phase, very high hydrophobicity and a significant pi-pi interaction. Ideal for the separation of high MW peptides and oligonucleic acids. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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MacroSep BIO-Gold PFP

MacroSep BIO Gold PFP – strongest pi-pi interaction of all the BIO Gold phases. The most hydrophilic of the BIOGold phenyl phases and may be used for fluorine modified biologics based upon a fluorophilicity interaction. MacroSep BIO Gold columns are manufactured utilizing tight process control of the silica, bonding and column packing processes. The reproducible column packing method control provides exceptional efficiency, symmetry and reproducibility. There are eight phases (see below) all available in 1.9μm, 3μm, 5μm and 10μm particle sizes. The 10μm material is available in bulk.

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Neptune dC18

Neptune™ dC18 is an alternative to the Waters Atlantis® dC18 material for reverse phase chromatography. In many cases Neptune™ has shown better retention and a longer column lifetime than the Atlantis®. Enhanced polar compounds will be retained with complete compatibility with aqueous mobile phases. Excellent for LC/MS and gradient research. Neptune™ phases are available in 3 micron, 5 micron, and 1.8 micron size particles:

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Neptune HILIC Silica

Neptune™ HILIC Silica is an alternative to the Waters Atlantis® HILIC Silica material for HILIC chromatography. In many cases Neptune™ has shown better retention and a longer column lifetime than the Atlantis®. Enhanced polar compounds will be retained with complete compatibility with aqueous mobile phases. Excellent for LC/MS and gradient research. Neptune™ phases are available in 3 micron, 5 micron, and 1.8 micron size particles:

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Neptune T3

Neptune™ T3 is an alternative to the Waters Atlantis® T3 material for reverse phase chromatography. In many cases Neptune™ T3 has shown better retention and a longer column lifetime than the Atlantis®. Enhanced polar compounds will be retained with complete compatibility with aqueous mobile phases. Excellent for LC/MS and gradient research. Neptune™ phases are available in 3 micron, 5 micron, and 1.8 micron size particles:

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Nucleosil C18

Nucleosil C18, manufactured by Macherey- Nagel, Germany, is spherical totally porous silica bonded with octadecyl silanes and is available in a wide range of pore sizes and particle sizes. It has been cited extensively in the literature and is very well regarded in the chromatography community. Nucleosil is well characterized and reproducible. ES Industries has extensive experience with Nucleosil packings and manufactures the highest quality Nucleosil columns available.

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Nucleosil C18 PAH

Nucleosil C18 PAH, manufactured by Macherey- Nagel, Germany, is spherical totally porous silica bonded with octadecyl silanes, is tuned for the separation of polycyclic aromatic hydrocarbons (PAH) and is available in a wide range of pore sizes and particle sizes. It has been cited extensively in the literature and is very well regarded in the chromatography community. Nucleosil is well characterized and reproducible. ES Industries has extensive experience with Nucleosil packings and manufactures the highest quality Nucleosil columns available.

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