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Chromegabond WR (Wide Range) is specially deactivated to produce superior peak shapes for amines and acids. Chromegabond WR C18 superior performance is the result of a multistep process beginning with ultra-pure synthetically produced spherical silica. The ultra-pure silica particles are then fully hydroxylated before they undergo an extensive bonding monomeric C18 alkyl chains, using proprietary bonding procedures. The bonded particles are then exhaustively endcapped to react any remaining silanol groups yielding columns that are much more resistant to degradation by acidic and basic mobile phase compositions, while improving peak shapes for amines and acids.