Preparative high-performance liquid chromatography (HPLC) and preparative supercritical fluid chromatography (SFC) are the methods of choice for the purification of large quantities of a diverse range of compounds.

ES Industries has designed a complete range of achiral and chiral columns for either purification by SFC or HPLC

Achiral GreenSep Columns for SFC

GreenSep™ stationary phases have been specifically engineered for Supercritical Fluid Chromatography (SFC) separations paying close attention to bonding coverage, density and all factors leading to high capacity phases, which exhibit excellent selectivity and peak shape. GreenSep columns, from analytical to preparative sizes, are available for all SFC phases in particle size from 3 – 20 μm and include our new high performance 15mm ID columns which have been designed to deliver high performance SFC separations.

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Achiral Preparative Columns for HPLC

Preparative chromatography is extremely powerful technique for the isolation of compounds from complex mixtures. At ES Industries we offer preparative chromatography columns in a variety of particle sizes, pore sizes, and stationary phases. These highly efficient preparative columns are compatible with today’s chemistries and analytical methodology. Our expertise in bonding chemistries and column packing technologies can deliver scalable chromatographic columns from analytical column formats up to 4 inch preparative diameters thus allowing for efficient transfer of methodologies from analytical columns to preparative columns.

All the chromatographic phases offered by ES Industries are available in preparative column formats. We offer lengths from 5 cm to 50 cm and several diameters including 10mm, 15mm, 25mm, 30 mm, 50 mm and 100 mm. Some our most popular stationary phases for reverse phase preparative columns are:

  • Epic C18 120A
  • Epic C4 SD 120A
  • Epic C18-SD 120A
  • Epic Polar 120A
  • Chromegabond WR C18 120A
  • AquaSep 100A
  • FluoroSep RP Phenyl 60A, 100A
  • MacroSep C18 300A
Chiral Columns for SFC and HPLC

Chirality has become critically important in the pharmaceutical, chemical and agricultural industries. The subtle differences that make compounds chiral can produce dramatically different pharmacological effects in biological systems. As a result, the demand for stereoselective separation techniques and analytical assays to evaluate the enantiomeric purity of chiral compounds has increased. Chiral chromatography in the forms of HPLC and SFC has become a necessary tool – not only for the analytical determination of enantiomeric purity, but also for the isolation and purification of enantiomers.

As a leader in chiral separations we are able to offer you a broad range of Chiral Stationary Phases (CSPs) for your analytical and preparative chromatography needs. Existing chiral stationary phases can separate a wide variety of chiral mixtures, however, there are still enantiomeric mixtures that are difficult to separate limiting their characterization. This provides our drive to develop new CSP’s with differing chiral selectivities.

  • Product Features Include:
  • Excellent Selectivity Range
  • Wide Range of Applications
  • Superior Resolution and Efficiency
  • High Pressure Limit
  • Fast Optimization
  • One column for both SFC and HPLC use