The chromatographic separation of chiral compounds is an important tool in the search for new pharmaceutical entities. Both HPLC and SFC separations of chiral chemicals are important tools for analytical determination and preparative isolation of enantiomeric mixtures. Existing chiral stationary phases can separate a wide variety of chiral mixtures. However there are still enantiomeric mixtures that are difficult to separate limiting their characterization. To expand the separation capabilities of chiral stationary phases we have developed a new halogenated carbohydrate based chiral stationary phase ChromegaChiral CC4 (cellulose tris(4- chloro-3-methylphenylcarbamate).