|
Chromegabond LS (Lipophilic Separations) has been developed for analysis of lipophilic analytes such as fat-soluble vitamins, fatty acids, aliphatic pharmaceutical, and surfactants. The development of this new stationary phase evolved from our experience with fluorine based stationary phases. We discovered that many lipophilic compounds such as fat-soluble vitamins can be analyzed using reversed phase conditions on fluorophases. Using our knowledge of fluoro-aliphatic phase with a proprietary fluoroendcapping. This new phase can produce chromatograms that are difficult to obtain on conventional ODS stationary phases or with short-chain hydrocarbon phases.
Chromegabond LS is a versatile phase, not only for lipophilic compounds, but for many analysis where run times need to shorten. In numerous applications Chromegabond LS may shorten analysis time considerably without any loss in resolution. In addition, Chromegabond LS is an excellent alternative to short chain alkyl chains because of its superior hydrolytic stability.
Order your column
Given its unique retention behavior, Chromegabond® LS presents a real challenge for the design of relevant and meaningful quality control testing. Conventional test probes and mobile phase conditions would generate QC chromatograms with short retention times for test components. These short retention times would not allow for the full interaction of the test probe with the stationary phase and the underlying silica surface.
In addition, conventional tests would fail to adequately demonstrate the quality of the bonded phase.
To ensure the quality of Chromegabond LS columns we developed QC tests containing compounds that could interact extensively with the bonded phase. After an intensive investigation we determined that fat soluble vitamins such as vitamin A palmitate would provide the most reliable QC test performance. These fat solublevitamins interact completely with the Chromegabond LS phase and ensure that we are producing the highest quality phase possible.
Chromegabond LS meets and exceeds the strict quality standards set for all ES Industries HPLC columns.
|
